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Four-year-old Zunaira is watching the animated childrens series Love Monster on an overhead TV screen as she lies in a hospital bed with six electrodes stuck to her body.Her 10-year-old brother Zain is busy on his iPad on a chair next to her in the clinical research facility at Great Ormond Street Hospital Gosh in central London, whose white walls have been brightened with reproductions of chi stanley spain ldrens drawings of leaves. They are here for a study trialling a new drug to treat a rare genetic kidney disorder that can be fatal.Electrocardiograms ECGs to measure the hearts activity and blood tests are performed before both children are injected with lumasiran to treat primary hyperoxaluria vaso stanley type 1 PH1 . The rare condition is caused by the buildup of oxalate, a substance normally filtered through the kidneys and expelled in urine. She gets very excited when she comes to the hospital because she gets treated like royalty, says Zunairas mother, Hafsah.Zunaira has been given the drug, initially every month and now every three months, since she was three months old, as part of a clinical trial that involves just five children. The results were so good that her brother Zain is getting the same drug on a compassionate basis, a rare treatment option that allows an unauthorised medicine to be used outside trials.Her treatment is novel for another reason: Zunaira is a participant in the increasingly rare field of commercial clinical trials in the UK.The dwindling nature of su stanley website ch pilots h Abeg PUBG drops Fortnite game lawsuit without explanation
A Chinese human rights activist has been camping out at Tokyo s international airport since 4 November because Beijing has barred him from re-entering China.Feng Zhenghu, a Shanghai-based activist, said in a phone conversation that he had been sleeping on a couch near the immigration checkpoint and surviving on food and water given to him by passing travellers.His sister, Natsuki Suzuki, who lives in Japan and is married to a Japanese national, said today Feng arrived stanley thermos in Japan in April. Since then, he has tried unsuccessfully to return to China stanley cup website eight times.Four times airlines prevented him from boarding, and four times 鈥?including his most recent attempt earlier this month 鈥?he got as far as Shanghai s Pudong airport, but Chinese authorities refused him entry and sent him back to Tokyo, Suzuki said.Fumio Ikeda, an immigration official, said Feng arrived from Shanghai on 4 November with a valid Chinese passport and a visa to enter Japan 鈥?but he has refused to leave Narita airport. I want to go back to China. I have no reason to stay in Japan stanley canada , Feng, 55, said by phone. He declined to say how long he would stay at the airport.Ikeda said Japanese officials cannot force him to leave the airport.Amnesty International has called Feng a prominent human rights defender in China. In 2001 he was sentenced to three years in prison for illegal business activity . Since his release in 2004 Feng has written critical pieces highlighting alleged malpractice by local gove |
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